Lab 5: Chemical Genetics
Movies & Lectures to Watch:
*Stuart Schreiber's Lecture on Chemical Genetics: http://www.hhmi.org/biointeractive/genomics/lectures.html
*Movies on Chemical Genetics: http://www.hhmi.org/biointeractive/genomics/animations.html
*Chemical screening movie
*Rampamycin movie
*How small molecule arrays are made
How Gleevec works: select 'Genes and Medicine', then 'drug design'. Select 'How Gleevec works' and run the
animations under "Watch the Clips".
To use in lab:
**PubChem: http://pubchem.ncbi.nlm.nih.gov/
ChemBank: http://chembank.broad.harvard.edu/welcome.htm
**ChemBank Quick Search: http://chembank.broad.harvard.edu/protein/quick-search.htm
Interesting sites to visit:
eMolecules (build your chemical structure): http://www.emolecules.com/index.php
All things Chemical Genetics: http://www.biochemweb.org/chemical.shtml
Learn more about Chemical Genetics:
About Chemical Genetics
**Broad Institute at MIT: Initiative for Chemical Genetics
Interviews with Chemical Genetics Researchers
| searchingfordrugs.pdf |
| pharmacogenetics.pdf |
